Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Work Done During Volume Change01:17

Work Done During Volume Change

In mechanics, work is done on an object when the force acting on it displaces the object. In thermodynamics, work done on a system can be estimated when the system's volume changes during any thermodynamic process.
Consider a gas confined to a cylinder fitted with a movable piston at one end. If the gas expands from volume V1 to volume V2, it exerts a force on the piston, such that the piston moves by a distance dr.
The work done by the gas on the piston can be expressed as
Scale-Up Processes01:14

Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...
Unsoundness of Aggregate due to Volume Change01:26

Unsoundness of Aggregate due to Volume Change

Unsoundness in aggregates due to volume changes is primarily caused by the physical alterations aggregates undergo, such as freezing and thawing, thermal changes, and wetting and drying. Unsound aggregates, when subjected to these changes, result in volume change upon disintegration. This, in turn, contributes to the deterioration of concrete, including scaling, pop-outs, and cracking. Particular types of aggregates, such as porous flints, cherts, and those containing clay minerals, are...
Manufacture of Concrete Masonry Units01:27

Manufacture of Concrete Masonry Units

The process of manufacturing concrete masonry units begins by mixing stiff concrete composed of Portland cement, aggregates, and water. This mixture is then poured into metal molds. To ensure the concrete settles uniformly and to avoid separation of its components, the mixture in the molds is subjected to vibration. Shortly after, the still-wet blocks are removed from the molds and placed on racks.
These wet blocks are then transported for curing, which can occur in one of two environments: a...
Design Example: Vintage Mixing Console01:17

Design Example: Vintage Mixing Console

A sound engineer at a music company recently encountered a problem. The output from their newly acquired studio's vintage mixing console was too low for the requirements of modern recording equipment. To rectify this situation, the engineer decided to design an audio pre-amplifier using an operational amplifier (op-amp) to boost the signal level.
The specifications for the pre-amplifier were clear. It needed to amplify the audio signal by a factor of 10, have an input impedance above 10...
Modified-Release Drug Delivery Systems: Rate-Programmed II01:19

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A prospective clinical trial to evaluate the microbial barrier of a needleless connector.

The Journal of hospital infection·2007
Same author

Incorporating microfabrication in diagnostic instruments.

Medical device technology·2006
Same author

Preventing leaks around a laryngeal mask airway.

Anaesthesia·2006
Same author

Community physiotherapy and other support services.

The Australasian nurses journal·1980

Related Experiment Video

Updated: Jul 17, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

Ramping up to volume manufacture.

S Burnell1

  • 1Cambridge Consultants Ltd, Cambridge, UK. simon.burnell@cambridgeconsultants.com

Medical Device Technology
|January 24, 2007
PubMed
Summary

Rapid product development and high-volume manufacturing are crucial for maintaining market share. This study identifies key decision-making issues and presents a technique using lateral-flow strips as an example.

Area of Science:

  • Manufacturing and Business Strategy
  • Product Development
  • Market Dynamics

Background:

  • Competitive markets necessitate rapid adaptation to consumer demands to sustain revenue and market share.
  • Failure to meet market demands quickly can lead to significant financial losses and erosion of market position.
  • Scaling up production to high-volume manufacturing is a critical strategic decision for businesses facing increasing demand.

Purpose of the Study:

  • To identify the critical issues associated with transitioning to high-volume manufacturing.
  • To present a practical technique for evaluating and managing the decision-making process for scaling production.
  • To use lateral-flow strips as a case study to illustrate the proposed technique.

Main Methods:

  • Analysis of strategic decision-making factors in competitive markets.

More Related Videos

A Soft Tooling Process Chain for Injection Molding of a 3D Component with Micro Pillars
05:32

A Soft Tooling Process Chain for Injection Molding of a 3D Component with Micro Pillars

Published on: August 4, 2018

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

Related Experiment Videos

Last Updated: Jul 17, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

A Soft Tooling Process Chain for Injection Molding of a 3D Component with Micro Pillars
05:32

A Soft Tooling Process Chain for Injection Molding of a 3D Component with Micro Pillars

Published on: August 4, 2018

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration
14:24

Manufacturing of Three-dimensionally Microstructured Nanocomposites through Microfluidic Infiltration

Published on: March 12, 2014

  • Development of a technique for assessing the feasibility of high-volume manufacturing.
  • Application of the technique using lateral-flow strips as a specific product example.
  • Main Results:

    • Key challenges in high-volume manufacturing decisions were identified.
    • A structured approach for evaluating manufacturing scale-up was proposed.
    • The lateral-flow strip example demonstrated the practical utility of the technique.

    Conclusions:

    • Strategic decision-making is vital for adapting to market demands and ensuring business growth.
    • A systematic technique can aid in navigating the complexities of high-volume manufacturing decisions.
    • The presented method offers a valuable framework for optimizing production scaling strategies.