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Updated: Jul 17, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Sudden sensorineural hearing loss and hemodialysis
Olawale A Lasisi1, Babatunde L Salako, Solomon Kadiri
1Department of Oto-Rhino-Laryngology, College of Medicine, University of Ibadan, and University College Hospital, Ibadan, Nigeria. sakeemng@yahoo.com
Sensorineural hearing loss (SNHL) in kidney failure patients may stem from hemodialysis complications. Two cases suggest osmotic changes or membrane contamination caused SNHL during treatment.
Area of Science:
- Nephrology
- Otolaryngology
- Toxicology
Background:
- Sensorineural hearing loss (SNHL) in patients with renal failure undergoing hemodialysis has an unclear etiology.
- Potential causes include shared kidney-lung antigens, hemodialysis-induced osmotic shifts, and diuretic ototoxicity.
Observation:
- Two cases of SNHL are presented in patients with renal failure undergoing hemodialysis.
- A 35-year-old male developed profound SNHL after 5 hemodialysis sessions.
- A 36-year-old female developed severe to profound SNHL after 7 hemodialysis sessions.
Findings:
- The observed SNHL in both patients is hypothesized to be linked to osmotic disequilibrium within the labyrinth.
- Alternatively, acute labyrinthine injury due to contamination from degraded cellulose acetate hemodialyzer membranes is considered.
Implications:
- These cases highlight potential ototoxic risks associated with hemodialysis, particularly with older membrane materials.
- Further research is needed to elucidate the precise mechanisms and prevent hearing loss in renal failure patients.
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