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Isolation and characterization of galanin from sheep brain
R Sillard1, U Langel, H Jörnvall
1Department of Biochemistry II, Karolinska Institutet, Stockholm, Sweden.
Peptides
|July 1, 1991
Abstract:
Galanin is a well-known, naturally occurring peptide, which has been characterized from both cDNA sequences and direct peptide analysis. Previous structural studies have been made using intestinally derived material. This report concerns galanin isolation from sheep brain and its sequence determination. Sheep galanin shows great similarity to pig galanin, differing by one amino acid substitution, that being a histidine residue, as in cow and rat galanin, instead of tyrosine at position 26.