Related Experiment Video
Updated: Jul 17, 2026

Use of a Monocyte Monolayer Assay to Evaluate Fcγ Receptor-mediated Phagocytosis
Published on: January 2, 2017
Congenital sensory neuropathy as a differential diagnosis for phagocytic immunodeficiency
Mohammad Gharagozlou1, Fariborz Zandieh, Parviz Tabatabaei
1Department of Immunology and Allergy, Children Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran. gharagoz@tums.ac.ir
Abstract:
There are few reports about congenital indifference to pain or Hereditary and Sensory Autonomic Neuropathy (HSAN). Several investigations for pathophysiology of this syndrome have been performed and different classifications about it. In this report we present a case of HSAN type II with general absence of pain and self amputations and leprosy-like damage of extremities which was suspected to be phagocytic immunodeficiency due to past history of repeated ulcer and abscess formation.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
