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Related Experiment Videos

Aspergillus mycotic aneurysm--case report.

Y Komatsu1, K Narushima, E Kobayashi

  • 1Department of Neurosurgery, Tsukuba Memorial Hospital, Ibaraki, Japan.

Neurologia Medico-Chirurgica
|June 1, 1991
PubMed
Summary
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A rare case of fungal aneurysm complicating trans-sphenoidal surgery is presented. Aspergillus infection of a carotid artery aneurysm led to subarachnoid hemorrhage, highlighting the risks of invasive fungal infections.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Trans-sphenoidal surgery for Rathke's cleft cyst can have rare complications.
  • Fungal aneurysms are uncommon but serious vascular complications.

Observation:

  • A 61-year-old female developed subarachnoid hemorrhage post-surgery.
  • Neuroradiology identified a large internal carotid artery aneurysm.
  • Autopsy revealed Aspergillus hyphae within the aneurysm wall.

Findings:

  • The case suggests direct fungal invasion into the aneurysm wall.
  • Two proposed pathways for fungal aneurysm development exist: meningitis-related (large, central) and sepsis-related (small, peripheral).
  • This case aligns with the meningitis-related pathway due to its size and location.

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Implications:

  • Ruptured fungal aneurysms are challenging to treat.
  • Early eradication of fungal meningitis or sepsis is crucial to prevent aneurysm formation.
  • This case underscores the importance of considering fungal infections in complex neurosurgical cases.