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Calcium phosphates formation on CaTiO3 coated titanium.

Naofumi Ohtsu1, Kenji Sato, Kesami Saito

  • 1Institute for Material Research, Tohoku University, 2-1-1 Katahira, Sendai 980-8577, Miyagi, Japan. nohtsu@imr.edu

Journal of Materials Science. Materials in Medicine
|January 24, 2007
PubMed
Summary

Calcium titanate (CaTiO3) coatings on titanium enhance hydroxyapatite (HAP) formation in simulated body fluid. Annealing CaTiO3 films deposited at room temperature significantly boosts HAP layer thickness, improving biocompatibility.

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Area of Science:

  • Biomaterials Science
  • Materials Chemistry
  • Surface Engineering

Background:

  • Titanium (Ti) is a widely used biomaterial for implants.
  • Enhancing the biocompatibility of titanium surfaces is crucial for osseointegration.
  • Calcium phosphate formation is a key indicator of biomaterial bioactivity.

Purpose of the Study:

  • To investigate the calcium phosphate formation on CaTiO3 coating films deposited on Ti.
  • To compare the bioactivity of CaTiO3 films prepared under different conditions.
  • To determine the optimal processing parameters for enhanced bioactivity.

Main Methods:

  • CaTiO3 thin films (50 nm) were deposited on Ti using radiofrequency (RF) magnetron sputtering at room temperature (RT) and 873 K.
  • Post-deposition annealing at 873 K in air for 7.2 ks was performed on RT-deposited films.

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  • Film characterization using grazing incident angle X-ray diffractometry (GI-XRD) and X-ray photoelectron spectroscopy (XPS).
  • Immersion in Hanks' balanced saline solution (HBSS) for 60 days to assess hydroxyapatite (HAP) formation.

    • Main Results:

    • Hydroxyapatite (HAP) formation was observed on CaTiO3 coated Ti after 60 days in HBSS.
    • A thicker HAP layer formed on CaTiO3 films deposited at RT and subsequently annealed compared to those deposited at 873 K.
    • Differences in HAP formation correlated with variations in the outermost surface chemical properties.

    Conclusions:

    • CaTiO3 thin films enhance the calcium phosphate formation ability on titanium surfaces.
    • Depositing CaTiO3 at room temperature followed by annealing at 873 K optimizes HAP formation.
    • This processing route offers a promising strategy for developing bioactive titanium implants.