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Related Experiment Video

Updated: Jul 17, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Periocular involvement in cutaneous leishmaniasis.

M Durdu¹, S Gökçe, M Bagirova

¹Department of Dermatology, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey. sivandr@hotmail.com

Journal of the European Academy of Dermatology and Venereology : JEADV

|January 25, 2007

Summary

Cutaneous leishmaniasis (CL) periocular involvement occurred in 2.9% of patients. Early diagnosis and treatment of CL lesions in the eye area are crucial to prevent deformities.

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Area of Science:

Dermatology
Ophthalmology
Infectious Diseases

Background:

Cutaneous leishmaniasis (CL) commonly affects the face, with periocular involvement occurring in 2-5% of cases.
Periocular CL lesions can be misdiagnosed due to their resemblance to other conditions.
Understanding the epidemiology and clinical presentation of periocular CL is essential for accurate diagnosis and management.

Purpose of the Study:

To determine the frequency of periocular involvement in CL in Turkey's Cukurova region.
To analyze the clinical characteristics, diagnostic methods, and treatment approaches for periocular CL.
To highlight the importance of early intervention in preventing ocular complications.

Main Methods:

Prospective evaluation of patients diagnosed with CL between December 1998 and December 2004.
Detailed assessment of lesion location, type, and patient demographics.
Documentation of any co-existing conditions like dacryocystitis and follow-up for complications.

Main Results:

Out of 2066 CL patients, 59 (2.9%) had periocular lesions (66 total lesions, 2.5%).
Lesion types included papular (48.5%), nodulo-ulcerative (22.7%), plaque (15.2%), and nodular (13.6%).
Four patients presented with dacryocystitis; no ocular or periocular deformities were observed during follow-up.

Conclusions:

Early evaluation and treatment of suspected CL are vital.
Prompt management can prevent permanent ocular and periocular deformities.
This study emphasizes the need for vigilance regarding periocular CL presentations.