Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

"Benign" hypertensive nephrosclerosis.

I Dasgupta1, C Porter, A Innes

  • 1Birmingham Heartlands Hospital, Bordesley Green East, Birmingham, B9 5SS. indranil.dasgupta@heartofengland.nhs.uk

QJM : Monthly Journal of the Association of Physicians
|January 25, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optima: a GUI-based toolkit for developing and validating interpretable machine learning based supervised classification QSAR models.

SAR and QSAR in environmental research·2026
Same author

Managing Blood Pressure in Dialysis Patients: A Summary of UK Clinical Practice Guideline.

Kidney international reports·2026
Same author

First report on machine learning based multiclass classification of Caco-2 permeability using different balancing strategies.

SAR and QSAR in environmental research·2025
Same author

A Pilot Randomised Controlled Trial to Compare 3D Printed Versus Conventionally Fabricated Complete Dentures.

The European journal of prosthodontics and restorative dentistry·2025
Same author

Fabry disease in the haemodialysis population: outcome of a UK screening study (SoFAH).

BMC nephrology·2025
Same author

Newborn screening follow-up for very long-chain acyl-CoA dehydrogenase deficiency in Colorado: Working towards a standardized protocol.

Molecular genetics and metabolism·2025
Same journal

Familial pulmonary fibrosis due to pathogenic TERT variant presenting with a UIP-PPFE phenotype.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Corkscrew Oesophagus Due to Distal Oesophageal Spasm.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Correction to: Integrated care management for patients following acute stroke: a systematic review.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Methodological concerns regarding blinding and long term efficacy of fire needle therapy for plaque psoriasis.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Media framing of GLP-1/GIP therapies in Japan: Lessons for aging universal health coverage systems.

QJM : monthly journal of the Association of Physicians·2026
Same journal

Regional heterogeneity in psoriasis area and severity index response to fire needle therapy for plaque psoriasis.

QJM : monthly journal of the Association of Physicians·2026
See all related articles

Biopsy-proven benign hypertensive nephrosclerosis (BHN) frequently leads to end-stage renal failure (ESRF). High blood pressure and initial serum creatinine levels during follow-up significantly impact renal survival and patient mortality.

Area of Science:

  • Nephrology
  • Pathology
  • Hypertension

Background:

  • The link between benign hypertensive nephrosclerosis (BHN) and end-stage renal failure (ESRF) remains debated.
  • Lack of biopsy confirmation in most clinical diagnoses hinders understanding.

Purpose of the Study:

  • To determine if biopsy-proven BHN is a cause of ESRF.
  • To analyze factors influencing renal and patient survival in BHN cases.

Main Methods:

  • Retrospective analysis of 60 biopsy-proven BHN cases over 20 years.
  • Follow-up duration averaged 6.7 years.
  • Analysis of renal function, survival rates, and influencing factors.

Main Results:

  • 72% of patients with declining renal function progressed to ESRF.

Related Experiment Videos

  • Renal survival was significantly impacted by initial serum creatinine and blood pressure.
  • Initial serum creatinine was the primary predictor of patient survival.

    • Conclusions:

    • Biopsy-proven BHN is associated with a high rate of ESRF.
    • BHN contributes significantly to patient mortality.
    • Blood pressure and renal function markers are critical for prognosis.