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Updated: Jul 17, 2026

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Published on: June 4, 2012
'Streptococcus milleri' aortic valve endocarditis and hepatic abscess
Rashid M Rashid1, Wajeeh Salah2, Jorge P Parada3,2
1MD PhD Program, Loyola University Chicago, Maywood, IL, USA.
Group C Streptococcus, specifically Streptococcus milleri, rarely infects humans. This case highlights Streptococcus milleri causing both endocarditis and liver abscess in a single patient, a rare occurrence.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Clinical Case Reports
Background:
- Group C streptococci are known animal pathogens but infrequent causes of human infections.
- Phenotypically small-colony variants of Streptococcus milleri are typically linked to suppurative conditions like liver abscesses.
- Bacteraemia and endocarditis are less frequently associated with Streptococcus milleri infections.
Observation:
- A rare case of human infection involving Streptococcus milleri is presented.
- The patient exhibited concurrent endocarditis and a liver abscess.
- Both conditions were attributed to the same Streptococcus milleri strain.
Findings:
- This report details a unique instance of Streptococcus milleri causing simultaneous endocarditis and liver abscess.
- The case underscores the potential for Streptococcus milleri to manifest in severe, disseminated infections.
- It challenges the typical presentation patterns of Streptococcus milleri infections.
Implications:
- This case expands the known spectrum of Streptococcus milleri-related human diseases.
- It may prompt reconsideration of diagnostic approaches for patients with unexplained endocarditis or liver abscesses.
- Further research into the virulence factors and pathogenic mechanisms of Streptococcus milleri is warranted.
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