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Updated: Jul 17, 2026

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
08:31

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

Published on: June 8, 2018

A third link connecting aging with double strand break repair.

William R Engels1, Dena Johnson-Schlitz, Carlos Flores

  • 1Genetics Department, University of Wisconsin, Madison, Wisconsin 53706, USA. wrengels@wisc.edu

Cell Cycle (Georgetown, Tex.)
|January 25, 2007
PubMed
Summary

Aging DNA repair mechanisms shift from simple end-joining to homologous repair as organisms age. This age-related change in double-strand break (DSB) repair pathway usage offers new insights into aging molecular basis.

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