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A case of HHV-8-associated HIV-negative primary effusion lymphoma in Moscow
D Shirokov1, E Kadyrova, M Anokhina
1Laboratory of Haematopoiesis Immunology, N.N.Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Russian Federation, Moscow, Russia.
Abstract:
Primary effusion lymphoma is a rare tumor of B-cell derivation which is associated with human herpes virus type 8 (HHV-8) in 100% and with human immunodeficiency virus (HIV) in most of cases. The paper describes the first case in Russia of HIV(-) HHV-8(+) Epstein-Barr virus (EBV)(+) primary effusion lymphoma in a male patient aged 56 years. The tumor was located in the pleural cavity. Interestingly, the patient was HIV-negative while having a positive tumor HHV-8 test. There are only 22 similar cases described worldwide.
