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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Apparent Weight01:09

Apparent Weight

True weight is the measure of the gravitational force acting on an object. However, if the object accelerates, its measured weight is different from its true weight. Similar observations can be made when the object is submerged in water. An object's weight in water is its apparent weight, which is equal to the difference between its true weight and the buoyant forces.
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
Variation in Acceleration due to Gravity near the Earth's Surface01:20

Variation in Acceleration due to Gravity near the Earth's Surface

An object's apparent weight is its weight measured by a spring balance at its location. It is different from its true weight, the force with which the Earth pulls it, because of the Earth's rotation. Mathematically, an object's apparent weight equals its true weight minus the centripetal force that keeps it in a circular motion along with the Earth's surface every 24 hours.
The difference between the true and apparent weights is proportional to the square of the Earth's angular speed. Since the...

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Related Experiment Video

Updated: Jul 17, 2026

A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
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Weight perception in neonate infants.

Michèle Molina1, Boris Guimpel, François Jouen

  • 1Laboratoire Psychologie des Actions Langagières et Motrices, Université de Caen, F-14000, Caen, France. michele.molina@unicaen.fr

Journal of Integrative Neuroscience
|January 25, 2007
PubMed
Summary

Newborn infants can detect object weight using touch, even without exploration. This tactile perception stems from the sensorimotor system

Area of Science:

  • Developmental Psychology
  • Neuroscience
  • Sensory Perception

Background:

  • Infants possess haptic object weight detection abilities.
  • The mechanisms underlying this ability in newborns are not fully understood.
  • Exploratory procedures are not yet developed in newborns.

Purpose of the Study:

  • To investigate how newborns discriminate object weight without prior exploration.
  • To explore the role of the sensorimotor system's primary variability in tactile perception.
  • To identify the specific sensorimotor parameters involved in weight discrimination.

Main Methods:

  • Habituation period with objects of differing weights (heavy or light).
  • Test period presenting an object of a novel weight.

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  • Analysis of sensorimotor activity: holding times, pressure amplitude, and frequency.

    • Main Results:

    • Newborns demonstrated the ability to discriminate between object weights.
    • Specific changes in sensorimotor parameters were observed during weight discrimination.
    • Tactile perception in neonates is linked to sensorimotor system variability.

    Conclusions:

    • Newborns can haptically differentiate object weights.
    • The sensorimotor system's inherent variability underpins early tactile perception.
    • Further research can explore the developmental trajectory of this sensory capacity.