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[Therapeutically induced immunodeficiency]
1Abteilung für Endokrinologie, Universität Frankfurt.
Therapeutically induced immundefects principally can be the result of pathophysiological influences on autoimmune diseases by immunomodulation on the one hand or loss of resistance against bacteria, fungi or viruses as a consequence of immunomodulation on the other hand. Further complications such as increasing incidence of neoplasms after long-term therapy, hypersensitivity reactions, especially damage of bone marrow, can be recognised after application of many different drugs. The immunesuppressive drugs are discussed in detail.
Therapeutically induced immundefects principally can be the result of pathophysiological influences on autoimmune diseases by immunomodulation on the one hand or loss of resistance against bacteria, fungi or viruses as a consequence of immunomodulation on the other hand. Further complications such as increasing incidence of neoplasms after long-term therapy, hypersensitivity reactions, especially damage of bone marrow, can be recognised after application of many different drugs. The immunesuppressive drugs are discussed in detail.