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Updated: Jul 17, 2026

Following the Dynamics of Structural Variants in Experimentally Evolved Populations
Published on: February 3, 2023
Molecular evolution and polymorphism in a random environment
1Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Abstract:
A model of multi-allelic selection in a random environment, the SAS-CFF model, is examined for compatability with allele frequency and genetic distance data acquired by electrophoresis. The symmetric version of the model tends to predict higher than observed levels of polymorphism unless substantial positive autocorrelations in the environment are postulated. The actual allele frequency configurations observed in nature are in rough agreement with those predicted by the SAS-CFF model. An approximate analysis of the transient properties of the SAS-CFF model shows that, in broad outline, the behavior is quite similar to that of the neutral model.
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