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Hyperammonemia in generalized Mycobacterium genavense infection after renal transplantation
S Nurmohamed1, A Weenink, H Moeniralam
1Renal Transplant Unit, Department of Internal Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam.
Abstract:
After solid organ transplantation, patients are susceptible to infection caused by uncommon pathogens due the immunosuppressive drug therapy. Here, we report the first case of disseminated Mycobacterium genavense infection in a HIV seronegative renal transplant patient. The most striking clinical feature was a decreased consciousness. Blood results revealed hyperammonemia with otherwise normal liver function. Occurrence of hyperammonemia and massive M. genavense infection has not been reported before.
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