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Updated: Jul 17, 2026

Adaptation at the Extremes of Life: Experimental Evolution with the Extremophile Archaeon Sulfolobus acidocaldarius
Published on: June 14, 2024
Proteins from extremophiles as stable tools for advanced biotechnological applications of high social interest
Marcella de Champdoré1, Maria Staiano, Mosè Rossi
1Institute of Protein Biochemistry, CNR, Italian National Research Council, Via Pietro Castellino, 111, 80131 Naples, Italy.
Abstract:
Extremophiles are micro-organisms adapted to survive in ecological niches defined as 'extreme' for humans and characterized by the presence of adverse environmental conditions, such as high or low temperatures, extreme values of pH, high salt concentrations or high pressure. Biomolecules isolated from extremophiles possess extraordinary properties and, in particular, proteins isolated from extremophiles represent unique biomolecules that function under severe conditions, comparable to those prevailing in various industrial processes. In this article, we will review some examples of recent applications of thermophilic proteins for the development of a new class of fluorescence non-consuming substrate biosensors for monitoring the levels of two analytes of high social interest, such as glucose and sodium.
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