Related Experiment Video
Updated: Jul 17, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
Published on: August 2, 2024
Prominent corneal nerves in a patient with multiple myeloma
Chirag Parghi1, G Tipton McKnight, Stephen C Pflugfelder
1Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Purpose:
To describe a case of prominent corneal nerves observed in a patient after diagnosis of multiple myeloma.
Methods:
Case report and literature review.
Results:
A 65-year-old woman with a history of multiple myeloma was referred for chronic epitheliopathy in the left eye. She was diagnosed with multiple myeloma 3 years before presentation and underwent treatment at that time. On examination, she was noted to have prominent corneal nerves bilaterally with absent corneal sensation.
Conclusion:
Multiple myeloma caused prominent corneal nerves and reduced corneal sensitivity.
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