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Updated: Jul 17, 2026

Daily Transfers, Archiving Populations, and Measuring Fitness in the Long-Term Evolution Experiment with Escherichia coli
Published on: August 18, 2023
Empirical fitness landscapes reveal accessible evolutionary paths
Frank J Poelwijk1, Daniel J Kiviet, Daniel M Weinreich
1FOM Institute AMOLF, Kruislaan 407, 1098 SJ, Amsterdam, The Netherlands.
Abstract:
When attempting to understand evolution, we traditionally rely on analysing evolutionary outcomes, despite the fact that unseen intermediates determine its course. A handful of recent studies has begun to explore these intermediate evolutionary forms, which can be reconstructed in the laboratory. With this first view on empirical evolutionary landscapes, we can now finally start asking why particular evolutionary paths are taken.
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