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Interleukin-18 and its three gene polymorphisms relating to allergic rhinitis

Sarka Sebelova1, Lydie Izakovicova-Holla2, Andrea Stejskalova2

  • 1Department of Pathophysiology, Faculty of Medicine, Masaryk University, Komenského nám. 2, 662 43, Brno, Czech Republic. ssebelova@chello.cz.

Journal of Human Genetics
|January 26, 2007
PubMed
Summary

Investigating single nucleotide polymorphisms (SNPs) in the IL-18 gene, this study found combined genotypes, not individual ones, were significantly associated with allergic rhinitis (AR). Specific IL-18 variants linked to Alternaria allergy and IgE levels in AR patients.

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