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Primary mediastinal anaplastic alk-1-positive large-cell lymphoma of T/NK-cell type expressing CD20

J Gonin1, H Kadiri, S Bensaci

  • 1Service Central d'Anatomie et Cytologie Pathologiques, Jacques Delarue, Hôtel-Dieu, 1, place du parvis Notre-Dame, 75181, Paris Cedex 04, France.

Virchows Archiv : an International Journal of Pathology
|January 26, 2007
PubMed

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...