Related Experiment Video
Updated: Jul 15, 2026

Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Does a positive neural margin affect outcome in facial nerve grafting?
1Department of Otolaryngology/Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon, USA. waxm@ohsu.edu
Background:
We sought to determine the effect of positive neural margins on subsequent facial nerve function following facial nerve grafting.
Methods:
In this retrospective review, 19 patients had sacrifice of their facial nerve with immediate facial nerve grafting, 8 had positive neural margins, and 11 had negative neural margins. Facial nerve function was analyzed using the House-Brackman scale.
Results:
In the first group (8 patients), 5 had positive proximal margins and 3 had positive distal neural margins. Outcome by House-Brackman score was III (2 patients), IV (3 patients), V (1 patient), and VI (2 patients). In the second group (no evidence of neural spread, 11 patients), outcome was III (3 patients), IV (2 patients), V (2 patients), and VI (4 patients).
Conclusion:
No significant difference in the outcome of facial nerve function was seen between these 2 groups. Facial nerve grafting should be considered in patients whose facial nerve is sacrificed, even when there is evidence of tumor in the perineurium at the margin of resection.

