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Non inherited hemoglobin anomalies
S P Dibenedetto1, G Russo Mancuso, A Di Cataldo
1Cattedra di Ematologia Pediatrica, Università di Catania, Italy.
A number of genetic or acquired conditions in which hemoglobin anomalies occur without detectable modifications of globin genes are reviewed. They include increased fetal hemoglobin (alpha 2 gamma 2), variations in hemoglobin A2 concentration, the presence of Hb H (beta 4), Bart's Hb (gamma 4), Hb Köelliker, glycosylated, carbamylated and acetylated hemoglobins.
A number of genetic or acquired conditions in which hemoglobin anomalies occur without detectable modifications of globin genes are reviewed. They include increased fetal hemoglobin (alpha 2 gamma 2), variations in hemoglobin A2 concentration, the presence of Hb H (beta 4), Bart's Hb (gamma 4), Hb Köelliker, glycosylated, carbamylated and acetylated hemoglobins.