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Updated: Jul 17, 2026

Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice
Published on: November 18, 2017
Seminal vesicle protein IV and its derived active peptides: a possible physiological role in seminal clotting
Salvatore Metafora1, Carla Esposito, Ivana Caputo
1CNR, Institute of Genetics and Biophysics Adriano Buzzati-Traverso, Naples, Italy.
Abstract:
Seminal vesicle protein 4 (SV-IV) is a highly flexible molecule that in aqueous solution behaves as a concentration-dependent self-associating system in which the degree of association (monomer <--> dimer <--> trimer equilibrium) seems to be related to its biological activities. This review reports the functional role of SV-IV in seminal clotting exerted through the modulation of inflammation, hemostasis, and sperm protection against the damage induced by immunological or reactive oxygen species during the long journey of spermatozoa in the female genital tract.
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