Related Experiment Video
Updated: Jul 17, 2026

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
Published on: November 10, 2023
[Avian influenza and the Severe Acute Respiratory Syndrome (SARS) - experiences and perspectives]
G Hoheisel1, W K Luk, J Winkler
1Die Institutsangaben sind am Ende des Beitrags gelistet. gerhard.hoheisel@t-online.de
Abstract:
New respiratory viruses associated with pneumonia have in the past few years been detected in humans. The sudden appearance of the severe acute respiratory syndrome (SARS) in 2003 demonstrated that an emerging and highly infectious disease caused by a hitherto unknown virus was able to spread rapidly, but could finally be contained by stringent measures. The avian influenza A-H5N1-virus of high pathogenicity has crossed in multiple instances the species barriers between humans, mammals, and birds posing a serious pandemic threat. The application of the so far learnt and the continued development of preventive strategies, efficient vaccines, and antiviral substances are besides worldwide surveillance decisive to rapidly detect the repeated, enforced, or new appearance of viruses like the SARS-CoV, influenza A-H5N1 virus, or of new viruses, to contain their spread, and to defeat them.
Insights
Emerging respiratory viruses like SARS and avian influenza pose significant threats. Continued development of preventive strategies, vaccines, and antivirals, alongside global surveillance, is crucial for containment.
Area of Science:
- Virology
- Epidemiology
- Public Health
Context:
- Recent emergence of novel respiratory viruses causing pneumonia in humans.
- Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 highlighted rapid spread of novel infectious agents.
- Avian Influenza A (H5N1) virus poses a pandemic threat due to interspecies transmission.
Purpose:
- To emphasize the importance of preparedness for emerging viral threats.
- To highlight the need for continued research and development in antiviral and vaccine technologies.
- To underscore the critical role of global surveillance in early detection and containment.
Summary:
- New respiratory viruses, including SARS-CoV and highly pathogenic avian influenza A (H5N1), have emerged, demonstrating rapid spread potential.
- Stringent containment measures were effective against SARS, but H5N1 poses an ongoing pandemic risk.
- A multi-pronged approach involving surveillance, prevention, vaccines, and antivirals is essential to combat these threats.
Impact:
- Informs public health strategies for managing emerging infectious diseases.
- Guides research priorities for vaccine and antiviral development.
- Stresses the necessity of international cooperation in disease surveillance and response.
Related Concept Videos
Coronavirus
Influenza
Viral Recombination
Respiratory Syncytial Virus Disease
Viral Mutations
Infectious Diseases and Their Occurrence

