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Related Experiment Video

Updated: Jul 17, 2026

One-anastomosis Gastric Bypass (OAGB) in Rats

One-anastomosis Gastric Bypass (OAGB) in Rats

Published on: November 10, 2018

Intragastric balloon for obesity.

M Fernandes¹, A N Atallah, B G O Soares

¹University of Medicine of Petropolis, Department of Clinical Surgery, Rua Almirante Saldanha, 184, Cremerie, Petrópolis, Rio de Janeiro, Brazil, 25645-230. iobesidade@uol.com.br

The Cochrane Database of Systematic Reviews

|January 27, 2007

Summary

Intragastric balloons (IGB) offer a safe weight loss option for obesity but show limited additional benefit over conventional treatments. Lifestyle changes remain crucial for sustained weight management.

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Area of Science:

Bariatric interventions
Obesity management
Gastroenterology

Background:

Obesity is a significant global public health challenge.
Intragastric balloons (IGB) are temporary devices for obesity treatment, particularly for those with high surgical risk or poor response to other methods.
The comparative effectiveness of IGB procedures versus conventional treatments is not well-established.

Purpose of the Study:

To evaluate the effects of intragastric balloon interventions in individuals with obesity.
To compare IGB efficacy against conventional obesity management strategies and different IGB techniques.

Main Methods:

Systematic review of randomized and quasi-randomized controlled trials.
Searches conducted across major databases (MEDLINE, EMBASE, LILACS, Cochrane Library) and expert consultations.
Inclusion criteria required a minimum follow-up of four weeks to assess short-term weight loss.

Main Results:

Nine trials with 395 patients were analyzed; most had follow-up under one year, and only a third had low risk of bias.
IGB did not demonstrate significantly greater weight loss compared to conventional management.
While generally safe, IGB placement increased the risk of minor complications like gastric ulcers and erosions.

Conclusions:

Limited evidence due to heterogeneity in IGB trials hinders definitive conclusions.
IGB appears safe, but its cost-effectiveness should be weighed against behavioral modification and diet programs.
Motivation and lifestyle changes are key co-adjuvants for successful weight loss and maintenance with or without IGB.