Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Therapy

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

Psychosis: Goals of Pharmacotherapy

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...

Antipsychotic Drugs: Therapeutic Uses and Side Effects

Antipsychotic Drugs: Therapeutic Uses and Side Effects

Antipsychotic drugs primarily block dopamine and serotonin receptors and cholinergic, adrenergic, and histaminergic receptors, thereby reducing hallucinations and delusions in conditions like schizophrenia. However, they can trigger unwanted extrapyramidal effects such as dystonias, Parkinson-like symptoms, and tardive dyskinesia.
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...

Schizophrenia

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...

Parkinson's Disease: Treatment

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neuropeptide Y and tuberoinfundibular dopamine activities are altered during lactation: role of prolactin.

Endocrinology·1999

Same author

Characteristics of delayed excretion of flavonoids in human urine after administration of Shosaiko-to, a herbal medicine.

Biological & pharmaceutical bulletin·1999

Same author

A long terminal repeat of the human endogenous retrovirus ERV-9 is located in the 5' boundary area of the human beta-globin locus control region.

Genomics·1999

Same author

Evaluation of a mucoadhesive buccal patch for delivery of peptides: in vitro screening of bioadhesion.

Drug development and industrial pharmacy·1999

Same author

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

Oncogene·1999

Same author

Cell-killing by paclitaxel in a metastatic murine melanoma cell line is mediated by extensive telomere erosion with no decrease in telomerase activity.

Oncology reports·1998

Search research articles

Related Experiment Video

Updated: Jul 17, 2026

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures

Published on: July 12, 2024

Morita therapy for schizophrenia.

Y He¹, C Li

¹Shanghai Mental Health Center, 600 Wan Ping Nan Lu, Shanghai, China, 200030. heyl@public9.sta.net.cn

The Cochrane Database of Systematic Reviews

|January 27, 2007

Summary

Morita therapy shows potential benefits for schizophrenia, including improved mental state and daily living abilities. However, current evidence is inconclusive, necessitating further research into this experimental intervention.

Area of Science:

Psychiatry
Clinical Psychology
Behavioral Therapy

Background:

Morita therapy, established in 1919 by Shoma Morita, is a structured behavioral program designed to enhance social functioning by fostering an outward perspective.
This therapy aims to improve an individual's engagement with life and social interactions.

Purpose of the Study:

To systematically evaluate the efficacy of Morita therapy in treating schizophrenia and schizophrenia-like psychoses.

Main Methods:

A comprehensive literature search was conducted across multiple databases, including the Cochrane Schizophrenia Group Trials Register, Chongqing VIP, and Wanfang.
Included studies were randomized clinical trials comparing Morita therapy against other treatments.
Data analysis involved calculating relative risks (RR) and weighted mean differences (WMD) with 95% confidence intervals (CI), and numbers needed to treat (NNT) where applicable.

More Related Videos

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Related Experiment Videos

Last Updated: Jul 17, 2026

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures

Modification of the Treatment Methods for Wasting Marmoset Syndrome with Tranexamic Acid and Supportive Measures

Published on: July 12, 2024

Development of a Virtual Reality Assessment of Everyday Living Skills

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 23, 2014

Main Results:

Eleven small, medium-to-poor quality studies (N=1041) were analyzed.
Morita therapy showed a trend towards improving mental state (RR 0.36, CI 0.1 to 0.9, NNT 5) compared to standard care.
Significant improvements were observed in the ability of daily living when Morita therapy was added to standard treatment (WMD -4.1, CI -7.7 to -0.6).
In specific comparisons, Morita therapy demonstrated better outcomes in mental state, insight, and social functioning.

Conclusions:

Existing trial data on Morita therapy for schizophrenia is currently inconclusive.
Morita therapy is considered an experimental intervention for schizophrenia, and further high-quality trials are warranted.
Specific guidelines for designing future studies are provided to enhance research rigor.