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Published on: October 16, 2021
Percutaneous mitral balloon valvotomy
1Adult Cardiology, King Faisal Heart Institute, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. fawzy100@hotmail.com
Abstract:
Percutaneous mitral balloon valvotomy (PMBV) was introduced in 1984 by Inoue who developed the procedure as a logical extension of surgical closed commissurotomy. Since then, PMBV has emerged as the treatment of choice for severe pliable rheumatic mitral stenosis (MS). With increasing experience and better selection of patient, the immediate results of the procedure have improved and the rate of complications declined. When the reported complications of PMBV are viewed in aggregate, complications occur at approximately the following rates: mortality (0-0.5%), cerebral accident (0.5-1%), mitral regurgitation (MR) requiring surgery (1.6-3%). These complication rates compare favorably to those reported after surgical commissurotomy. Several randomized trials reported similar hemodynamic results with PMBV and surgical commissurotomy. Restenosis after PMBV ranges from 4 to 70% depending on the patient selection, valve morphology, and duration of follow up. Restenosis was encountered in 21% of the author's series at mean follow-up 6 +/- 4.5 years and the 10 and 15 years restenosis-free survival rates were (70 +/- 3)% and (44 +/- 5)%, respectively, and were significantly higher for patients with favorable mitral morphology (85 +/- 3% and 65 +/- 6%), respectively (P < 0.0001). The 10 and 15 years event-free survival rates were (79 +/- 2)% and (43 +/- 9)% and were significantly higher for patients with favorable mitral morphology (88 +/- 2)% and (66 +/- 6)%, respectively (P < 0.0001). The effect of PMBV on severe pulmonary hypertension, concomitant severe tricuspid regurgitation, left ventricular function, left atrial size, and atrial fibrillation are addressed in this review. In addition, the application of PMBV in specific clinical situations such as in children, during pregnancy and for restenosis is discussed.
Insights
Percutaneous mitral balloon valvotomy (PMBV) is a safe and effective treatment for severe mitral stenosis. Favorable mitral morphology significantly improves long-term outcomes and reduces restenosis rates.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Percutaneous mitral balloon valvotomy (PMBV) was developed in 1984 as an alternative to surgical mitral commissurotomy.
- PMBV is the preferred treatment for severe, pliable rheumatic mitral stenosis (MS).
- Patient selection and procedural experience have improved PMBV outcomes and reduced complication rates.
Purpose of the Study:
- To review the efficacy and safety of PMBV for severe mitral stenosis.
- To analyze complication rates, restenosis rates, and long-term survival after PMBV.
- To discuss the impact of PMBV on associated cardiac conditions and its application in specific patient groups.
Main Methods:
- Review of existing literature and reported complication rates.
- Analysis of long-term follow-up data, including restenosis-free and event-free survival.
- Evaluation of hemodynamic results and effects on secondary cardiac conditions.
Main Results:
- PMBV exhibits low complication rates: mortality (0-0.5%), cerebral accident (0.5-1%), and MR requiring surgery (1.6-3%).
- Restenosis rates vary (4-70%), but favorable mitral morphology is associated with significantly higher 10 and 15-year restenosis-free survival (85-65%) and event-free survival (88-66%).
- PMBV demonstrates comparable hemodynamic results to surgical commissurotomy.
Conclusions:
- PMBV is a safe and effective treatment for severe mitral stenosis with favorable long-term outcomes.
- Patient selection, particularly favorable mitral morphology, is crucial for optimizing results and minimizing restenosis.
- The review addresses PMBV's effects on pulmonary hypertension, tricuspid regurgitation, and its use in children, pregnancy, and restenosis management.
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