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Updated: Jul 17, 2026
09:26
DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
Published on: December 29, 2021
A designed RNA shuts down transcription
Julia E Weigand1, Beatrix Suess
1Lehrstuhl für Mikrobiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Staudtstr. 5, 91058 Erlangen, Germany.
Chemistry & Biology
|January 27, 2007
Abstract:
Using an in vivo selection strategy, Kehayova and Liu identified an RNA molecule capable of silencing gene transcription in yeast . In doing so, they expand the repertoire of RNA molecules performing long-believed "protein-only" cellular functions.
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01:53Bacterial Transcription
RNA polymerase (RNAP) carries out DNA-dependent RNA synthesis in both bacteria and eukaryotes. Bacteria do not have a membrane-bound nucleus. So, transcription and translation occur simultaneously, on the same DNA template.
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