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Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Surgery is the best treatment for primary coarctation in the majority of cases
1Pediatric Heart Center, University of California, San Francisco, California 94143, USA. karlt@surgery.ucsf.edu
Insights
Surgical repair of coarctation offers superior long-term efficacy compared to interventional methods like balloon angioplasty and stenting. Current evidence suggests surgery remains the preferred treatment for primary coarctation.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Coarctation repair involves surgical and interventional techniques, prompting evaluation of their respective indications, risks, and success criteria.
- Surgical treatment demonstrates excellent long-term efficacy, with 88-96% freedom from re-intervention at 5 years for infants operated on early.
Observation:
- Balloon angioplasty has higher risks of aneurysm, aortic rupture, and residual pressure gradients (up to 20.7%).
- Stenting presents concerns regarding material, re-expandability with aortic growth, and serious complications like aneurysms, dissections (4.3%), and cerebral vascular injury (9%).
Findings:
- No interventional approach has proven superior to surgery for primary coarctation repair.
- Surgical results show favorable long-term outcomes that surpass the short-term benefits of angioplasty and stenting.
Implications:
- Surgical treatment is recommended for primary coarctation due to its established long-term efficacy and safety profile.
- Interventional techniques should be reserved for carefully selected cases where surgical risks are high or other options have failed.
Abstract:
Today, the availability of competing techniques for coarctation repair, including numerous surgical approaches as well as interventional ones, raises important questions about indications, risks and criteria for procedural success. Surgical treatment of coarctation is an extremely well tolerated procedure with excellent long-term efficacy due to an 88 to 96% 5 years freedom from re-intervention in patients operated on within the first months of life. If compared with surgery, balloon angioplasty features a higher risk for aneurysm formation, aortic rupture and a lower degree of success, with potentially important residual pressure gradient in up to 20.7% of patients. Stents are believed to overcome the problems of simple dilation, but concerns remain about the materials and the potential of re-expandibility in view of the growth of the treated aorta. Moreover, serious complications, including death, have been reported by stent implantation as well, similar to aneurysms or dissections (4.3%), balloon rupture with stent migration or cerebral vascular injury (9%). There is no evidence to date for the superiority of any interventional approach to surgical treatment of primary coarctation. The favorable long-term surgical results outweigh the proposed short-term benefits of angioplasty and stenting, which should be restricted to well selected cases.
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