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[Efficiency of mechanical plasmapheresis].

G Matthes¹, I Pawlow, E Richter

¹Institut für Transfusiologie und Transplantologie, Medizinischen Fakultät (Charité), Humboldt-Universität zu Berlin.

Beitrage Zur Infusionstherapie = Contributions to Infusion Therapy

|January 1, 1991

Summary

Automated donor plasmapheresis devices were evaluated for efficiency and reliability. The Ultralite-PCS demonstrated superior performance for routine use compared to Autopheresis-C A 100 and Plasmapur-Monitor.

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Area of Science:

Transfusion Medicine
Blood Component Collection

Background:

Plasmapheresis is a critical procedure for collecting plasma.
Automated devices offer potential advantages in efficiency and safety over manual methods.
Evaluating the performance of different automated plasmapheresis systems is essential for optimizing blood collection practices.

Purpose of the Study:

To compare the efficiency, reliability, and plasma quality of three automated donor plasmapheresis devices (Autopheresis-C A 100, Plasmapur-Monitor, Ultralite-PCS) against manual plasmapheresis.
To assess the suitability of these devices for routine clinical application.
To investigate the impact of plasmapheresis using the Plasmapur-Monitor on specific laboratory parameters.

Main Methods:

A clinical study involving 2,372 donor plasmaphereses.
Comparative analysis of automated devices (Autopheresis-C A 100, Plasmapur-Monitor, Ultralite-PCS) and manual plasmapheresis.
Evaluation of device efficiency, reliability, breakdown susceptibility, and collected plasma quality.
Monitoring of laboratory parameters during plasmapheresis with Plasmapur-Monitor.

Main Results:

The Ultralite-PCS device was found to be superior to the Autopheresis-C A 100 and Plasmapur-Monitor for routine plasmapheresis.
All tested automated devices showed varying degrees of efficiency and reliability.
The quality of fresh plasma collected by the automated devices was assessed.
Specific laboratory parameter changes during Plasmapur-Monitor plasmapheresis were documented.

Conclusions:

Machine plasmapheresis is recommended for routine operation.
The Ultralite-PCS is the preferred device, followed by Autopheresis-C A 100, and then Plasmapur-Monitor.
Further studies may be warranted to explore specific device-related impacts on laboratory parameters.

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