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Are statins associated with decreased tooth loss in chronic periodontitis?
Barry G Saver1, Philippe P Hujoel, Joana Cunha-Cruz
1Department of Family Medicine, University of Washington, Seattle, WA, USA. barry.saver@umassmed.edu
Aim:
To evaluate whether statin use was associated with decreased tooth loss among patients with chronic periodontitis.
Material And Methods:
We evaluated administrative health plan data from 1996 to 2002 covering dental and periodontal treatment utilization, dental extractions, and prescription medication fills of 12,631 adults aged 48-64 in 2002. With tooth loss as the outcome, we evaluated a number of different patterns of statin prescription across time in multivariate generalized linear models.
Results:
Unadjusted, statin use was associated with increased tooth loss. After adjustment for potential confounders, there was no suggestion of either increased or decreased tooth loss associated with statin use.
Conclusions:
Statin use was not associated with either a decreased or an increased risk of tooth loss.
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