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Updated: Jul 17, 2026

Measurement of Pulse Propagation Velocity, Distensibility and Strain in an Abdominal Aortic Aneurysm Mouse Model
Published on: February 23, 2020
Flow behaviour in an asymmetric compliant experimental model for abdominal aortic aneurysm
Valerie Deplano1, Yannick Knapp, Eric Bertrand
1IRPHE UMR 6594, Equipe de Biomécanique Cardiovasculaire, Marseille, France. deplano@irphe.univ-mrs.fr
Abstract:
An experimental study was carried out on asymmetrical abdominal aortic aneurysm (AAA) to analyse the physiological flows involved. Velocity measurements were performed using particle image velocimetry. Resting and exercise flow rates were investigated in models with rigid and compliant walls to assess the parameters affecting the flow behaviour. The secondary flow patterns, and especially the evolution of the vortices within the AAA, were found to be highly dependent on both the flow waveforms and the wall behaviour. Vortices impacts on the distal walls of the AAA occur in the compliant model and can increase the local pressure on the AAA walls and thus increase the wall stresses; AAA wall stresses are one of the most important factors contributing to ruptured aneurysm.
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