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Complications of pediatric EGD: a 4-year experience in PEDS-CORI
Kalpesh Thakkar1, Hashem B El-Serag, Nora Mattek
1Section of Pediatric Gastroenterology, Department of Hepatology and Nutrition, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas 77030, USA.
Insights
Pediatric esophagogastroduodenoscopy (EGD) has a 2.3% immediate complication rate, primarily reversible hypoxia. Risk factors include young age, higher American Society of Anesthesiologists (ASA) class, female sex, and intravenous sedation.
Area of Science:
- Pediatric Gastroenterology
- Medical Device Safety
- Clinical Outcomes Research
Background:
- Inconsistent estimates exist regarding the incidence and types of complications associated with pediatric esophagogastroduodenoscopy (EGD).
- Understanding these complications is crucial for improving patient safety in pediatric endoscopy.
Purpose of the Study:
- To determine the frequency of immediate complications during pediatric EGD.
- To identify factors influencing the occurrence of these complications in children.
Main Methods:
- A cross-sectional database study was conducted across 13 pediatric facilities utilizing the PEDS-CORI system.
- Data from 10,236 EGD procedures in children aged 0-18 years, performed between November 1999 and December 2003, were analyzed.
- Complications were identified and analyzed in relation to procedure indication, ASA class, sex, age, anesthesia type, and need for unplanned interventions.
Main Results:
- The overall immediate complication rate for pediatric EGD was 2.3% (239/10,236 procedures).
- Hypoxia (1.5%) and bleeding (0.3%) were the most frequent complications, all of which were nonfatal and reversible.
- Complication rates were significantly higher in younger children, those with higher ASA class, females, and patients receiving intravenous sedation.
Conclusions:
- The immediate complication rate for pediatric EGD is 2.3%, with hypoxia being the most common and reversible issue.
- Younger age, higher ASA class, female sex, and intravenous sedation are identified as significant risk factors for complications.
- While the study provides valuable insights, limitations include a lack of specific details and explicit criteria for reported complications.
Background:
Available estimates of the incidence and type of complications during pediatric EGD are inconsistent.
Objective:
To determine the frequency and the determinants of immediate complications during EGD in children.
Design:
We conducted a cross-sectional database study.
Setting:
The study involved 13 pediatric facilities that use the PEDS-CORI (Pediatric Endoscopy Database System Clinical Outcomes Research Initiative).
Patients:
Children (0-18 years) who underwent EGD at 13 facilities between November 1999 and December 2003.
Main Outcome Measurements:
We identified complications (recorded shortly after the procedure) and analyzed their occurrence with respect to procedure indication, American Society of Anesthesiologists (ASA) class, sex, age, anesthesia type, and unplanned interventions.
Results:
We analyzed 10,236 procedures performed in 9234 patients. Immediate complications were reported in 239 procedures (2.3%, 95% confidence interval 2.0%-2.6%). The most common complications were hypoxia (157 [1.5%]) and bleeding (28 [0.3%]). Complication rates were significantly higher in the youngest age group, highest ASA class, female gender, intravenous (IV) sedation group, and in the presence of a fellow.
Limitations:
The study is limited by a lack of specific details and explicit criteria for reported complications.
Conclusions:
The overall immediate complication rate of pediatric EGD is 2.3%. All complications were nonfatal, and most were hypoxia related (157/239 [66%]) and reversible. Young age, higher ASA class, female sex, and IV sedation are risk factors for developing complications.
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