Complications of pediatric EGD: a 4-year experience in PEDS-CORI

Kalpesh Thakkar1, Hashem B El-Serag, Nora Mattek

  • 1Section of Pediatric Gastroenterology, Department of Hepatology and Nutrition, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas 77030, USA.

Insights

Pediatric esophagogastroduodenoscopy (EGD) has a 2.3% immediate complication rate, primarily reversible hypoxia. Risk factors include young age, higher American Society of Anesthesiologists (ASA) class, female sex, and intravenous sedation.

Area of Science:

  • Pediatric Gastroenterology
  • Medical Device Safety
  • Clinical Outcomes Research

Background:

  • Inconsistent estimates exist regarding the incidence and types of complications associated with pediatric esophagogastroduodenoscopy (EGD).
  • Understanding these complications is crucial for improving patient safety in pediatric endoscopy.

Purpose of the Study:

  • To determine the frequency of immediate complications during pediatric EGD.
  • To identify factors influencing the occurrence of these complications in children.

Main Methods:

  • A cross-sectional database study was conducted across 13 pediatric facilities utilizing the PEDS-CORI system.
  • Data from 10,236 EGD procedures in children aged 0-18 years, performed between November 1999 and December 2003, were analyzed.
  • Complications were identified and analyzed in relation to procedure indication, ASA class, sex, age, anesthesia type, and need for unplanned interventions.

Main Results:

  • The overall immediate complication rate for pediatric EGD was 2.3% (239/10,236 procedures).
  • Hypoxia (1.5%) and bleeding (0.3%) were the most frequent complications, all of which were nonfatal and reversible.
  • Complication rates were significantly higher in younger children, those with higher ASA class, females, and patients receiving intravenous sedation.

Conclusions:

  • The immediate complication rate for pediatric EGD is 2.3%, with hypoxia being the most common and reversible issue.
  • Younger age, higher ASA class, female sex, and intravenous sedation are identified as significant risk factors for complications.
  • While the study provides valuable insights, limitations include a lack of specific details and explicit criteria for reported complications.
Abstract

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