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Pasteurella multocida urinary tract infection in a pediatric patient with end-stage renal disease

Josef Misael C Cortez1, Abubakr A Imam, Jocelyn Y Ang

  • 1Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, MI, USA.

The Pediatric Infectious Disease Journal
|January 30, 2007
PubMed

Insights

Pasteurella multocida, a common oral bacteria in pets, can cause urinary tract infections, especially in individuals with underlying health issues like kidney disease. This case highlights successful antibiotic treatment for a pediatric patient, emphasizing risk factors for such infections.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Nephrology

Background:

  • Pasteurella multocida is a Gram-negative bacillus commonly found in the oral flora of domestic animals like cats and dogs.
  • Infections typically manifest as soft tissue infections following animal bites or scratches.
  • Urinary tract infections (UTIs) caused by P. multocida are rare, particularly in pediatric populations.

Observation:

  • A case report details a 13-year-old boy with end-stage renal disease on peritoneal dialysis who developed a P. multocida UTI.
  • The patient's infection was successfully treated with a course of intravenous ampicillin-sulbactam followed by oral amoxicillin-clavulanate.
  • A literature review identified 13 additional cases of P. multocida UTI, including 12 adults and one other pediatric patient.

Findings:

  • Underlying medical conditions, such as end-stage renal disease, are significant risk factors for developing P. multocida UTIs.
  • Structural urologic abnormalities were also identified as contributing factors in reported cases.
  • P. multocida UTIs can occur in both pediatric and adult patients, though they are infrequent.

Implications:

  • This case underscores the importance of considering P. multocida in the differential diagnosis of UTIs, especially in immunocompromised patients or those with predisposing urologic conditions.
  • Effective antibiotic regimens, including ampicillin-sulbactam and amoxicillin-clavulanate, can successfully treat P. multocida UTIs.
  • Further research into the epidemiology and risk factors for P. multocida UTIs may improve early detection and management strategies.

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