Related Experiment Video
Updated: Jul 17, 2026

Quantification of Metal Leaching in Immobilized Metal Affinity Chromatography
Published on: January 17, 2020
Profiling of metal ions leached from pharmaceutical packaging materials
Kyle A Fliszar1, David Walker, Leonardo Allain
1Merck Manufacturing Division, West Point, PA 19486, USA. kyle_fliszar@merck.com
Abstract:
Metal leachables from packaging components can affect the safety and efficacy of a pharmaceutical formulation. As liquid formulations continue to contain surfactants, salts, and chelating agents coupled with lower drug levels, the interaction between the formulation and the packaging material becomes more important. This study examines the interaction of commonly used packaging materials with extraction solvents representative of liquid formulations found in the pharmaceutical industry stressed under conditions encountered during accelerated stability studies.
More Related Videos
09:51Standards for Quantitative Metalloproteomic Analysis Using Size Exclusion ICP-MS
Published on: April 13, 2016
10:31Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
Published on: December 6, 2015
Related Concept Videos
Extraction: Advanced Methods
Qualitative Analysis
For instance, group IV...
Electrodeposition
Electrodeposition can...