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Modulation of humoral immune responses by Tinospora malabarica in experimental animals
S K Bhattacharya1, P C Maity, P Mediratta
1Department of Pharmacology, University College of Medical Sciences & GT Hospital, Delhi, India.
Indian Journal of Experimental Biology
|October 1, 1991
Abstract:
Effect of alkaloidal fraction of aqueous extract of T. malabarica (Tm) was studied on humoral antibody responses in rats and guineapigs. The anti-SRBC haemagglutination titre was found to be enhanced in rats pretreated with Tm (2.5 mg/kg). Passive cutaneous anaphylaxis (PCA) in rats was also increased in Tm treated group. In vitro experiments with sensitized rat peritoneal mast cells showed a significant decrease in antigen-induced various spasmogens on isolated guineapig ileum.