Association of atrial fibrillation in patients with interatrial block over prospectively followed controls with

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Vignendra Ariyarajah1, Sirin Apiyasawat, Jaxon Fernandes

  • 1Division of Cardiology, Department of Medicine, St. Boniface General Hospital, University of Manitoba, Winnipeg, Manitoba, Canada. vignendra@hotmail.com

The American Journal of Cardiology
|January 31, 2007
PubMed

Insights

Interatrial block (IAB), a P wave abnormality, is linked to atrial fibrillation (AF). While IAB showed association with future AF events, it was not an independent predictor in this study.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Interatrial block (IAB) is a P wave abnormality associated with atrial fibrillation (AF).
  • The role of echocardiographic parameters, like left atrial enlargement, in this association requires further investigation.

Purpose of the Study:

  • To assess the relevance of IAB and echocardiographic parameters in predicting future AF events.
  • To determine if IAB is an independent predictor of AF in patients with comparable left atrial size and left ventricular ejection fraction.

Main Methods:

  • Retrospective analysis of 32 patients evaluated for IAB.
  • 15-month follow-up for cardiovascular events, atrial tachyarrhythmias (AF/atrial flutter), and death.
  • Logistic regression analysis to identify independent predictors of AF.

Main Results:

  • Preexisting AF and IAB were significantly associated with future AF events (p=0.02).
  • IAB was not an independent predictor of future AF; only preexisting atrial tachyarrhythmias were (HR 39.5, p=0.007).
  • IAB remained associated with AF after 15 months in patients with similar echocardiographic parameters.

Conclusions:

  • In patients with comparable echocardiographic parameters, IAB is associated with AF.
  • Further research is needed to confirm the extent of the association between IAB and AF.

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