Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Language activation studies with positron emission tomography.

R Wise1, U Hadar, D Howard

  • 1MRC Cyclotron Unit, Hammersmith Hospital, London, UK.

Ciba Foundation Symposium
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigating the impact of adipose derived media on ovarian cancer: Insights from a 3D in-silico model.

Mathematical biosciences·2026
Same author

Recommendations for tracking the residual forearm in people with trans-radial limb difference using marker-based motion capture.

Medical engineering & physics·2025
Same author

Introducing an adjustable upper limb prosthesis into a Ugandan clinical service: impacts on free living behaviour and prosthetic use.

Scientific reports·2025
Same author

An experimental toolbox for the physical characterization of thermal insulating polymeric foams.

Heliyon·2024
Same author

Adapting lean methodology towards surgical tray rationalisation in inguinoscrotal day case surgery in the republic of Ireland.

Journal of pediatric urology·2023
Same author

Negative pressure ventilation protects the brain.

Critical care (London, England)·2022

Positron emission tomography (PET) reveals brain regions activated during language tasks. Specific areas like the superior temporal gyri and prestriate cortex show activation during word processing and speech.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Psycholinguistics

Background:

  • Behavioral tasks induce changes in regional cerebral blood flow (rCBF) due to increased neural activity.
  • Positron emission tomography (PET) is a key neuroimaging technique for measuring these rCBF changes.

Purpose of the Study:

  • To investigate regional brain activation patterns associated with various language processing tasks using PET.
  • To correlate observed cerebral activation with established information-processing models of speech and reading.

Main Methods:

  • Utilized PET scans to measure regional cerebral blood flow (rCBF) during distinct language-based behavioral tasks.
  • Tasks included auditory processing (word repetition, non-word listening, category judgments) and visual processing (symbol/word strings).

Related Experiment Videos

  • Examined brain activation during verb retrieval and articulation tasks.

    • Main Results:

    • Significant activation observed in both superior temporal gyri during auditory word tasks.
    • Prestriate cortex activation occurred with visual presentation of letter strings and words; left medial prestriate cortex showed additional activation for non-words and real words.
    • Left posterior superior temporal gyrus (PSTG), left dorsolateral prefrontal cortex (DLPFC), and supplementary motor area (SMA) were engaged during verb retrieval; primary sensorimotor cortex activated during articulation.

    Conclusions:

    • PET studies reveal distinct neural networks involved in different aspects of language processing, including auditory, visual, and generative tasks.
    • Left PSTG and DLPFC are of particular interest for their roles in single-word comprehension and generation.
    • Task design is critical for accurately interpreting brain activation patterns in language studies.