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Study on the Metabolism of Six Systemic Insecticides in a Newly Established Cell Suspension Culture Derived from Tea (Camellia Sinensis L.) Leaves
Published on: June 15, 2019
[The study of the oil extract of tea leaf possible teratogenic and embriotoxical action]
V Khvedelidze1, B Butskhrikidze, D Gordeladze
1Akaki Tsereteli State University; The centre of scientistic national academy of Kutaisi.
Abstract:
The aim of the study was the investigation of possible embriotoxic and teratogenic action of small tea leaf oil extract (TLOE)--a new medicinal agent. The study of embriotoxic and teratogenic properties of TLOE was carried on the 20-day's white rat's young (150g-160g) and males (200g-250g). Experiment included selection of animals and their connubium; definition of the first day of pregnancy; introduction of a drug pregnant female; survey of embryos; processing of embryos, revealing of infringements in an internals and osteal system; statistical processing and comparison of results in relation to the intact control. The results of examination of tea leaf oil extract show no teratogenic and embriotoxic action in peroral therapeutic dose of 737 mg/kg .
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