Iridoids from Scaevola racemigera1.

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Scaevola racemigera Däniker is a plant species with potential medicinal properties.
• Iridoids are a class of monoterpenes found in various plant species, known for their diverse biological activities.
• The chemical constituents of *Scaevola racemigera* have not been extensively studied.

Purpose of the Study:

• To isolate and identify iridoid compounds from the aerial parts of *Scaevola racemigera*.
• To elucidate the structure of any novel compounds discovered.
• To contribute to the phytochemical knowledge of the *Scaevola* genus.

Main Methods:

• Extraction of compounds from the aerial parts of *Scaevola racemigera*.
• Chromatographic techniques for isolation and purification of iridoids.
• Spectroscopic analysis, including proton Nuclear Magnetic Resonance ((1)H-NMR) and carbon-13 Nuclear Magnetic Resonance ((13)C-NMR), for structure elucidation.

Main Results:

• Five iridoids were successfully isolated: loganin, loganic acid, sylvestroside III, cantleyoside, and scaevoloside.
• Scaevoloside was identified as a novel iridoid compound.
• The structure of scaevoloside was determined using comprehensive (1)H- and (13)C-NMR spectral data.

Conclusions:

• The aerial parts of *Scaevola racemigera* are a source of diverse iridoid compounds.
• The discovery of scaevoloside expands the known repertoire of iridoids.
• This study provides valuable phytochemical data on *Scaevola racemigera*, potentially informing future research into its bioactivity.