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Updated: Jul 17, 2026

An Efficient and Rapid HPLC-QQQ-MS Method for the Quantitation of Tropane Alkaloids in Medicinal Plants
Published on: June 12, 2026
Alkaloids from Rauwolfia cubana Stem Bark
J A Martinez1, C Gomez, T Santana
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Havana, San Làzaro y L, Ciudad de la Havana 4, Cuba.
Abstract:
Six indole alkaloids, tetrahydroalstonine, aricine, 16- EPI-affinine, ajmaline, amerovolfine, and amerovolficine have been isolated from the ethanolic extract of the stem bark of RAUWOLFIA CUBANA A. DC. Amerovolfine ( N(alpha)-demethylaccedine) and amerovolficine (16-demethoxy-carbonylpagicerine) are new alkaloids related to 16- EPI-affinine, and their structures have been determined by spectroscopic analysis.
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