Related Experiment Videos
Etodolac-induced pigmenting fixed drug eruption
Clinical and Experimental Dermatology
|February 1, 2007
Abstract
No abstract available in PubMed .
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Allergic Drug Reactions
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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...