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Related Experiment Video

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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Oral phaeohyphomycosis.

S V Cardoso¹, S S Campolina, A L S Guimarães

¹Oral Diagnosis Unit, State University of Montes Claros, Montes Claros, Brazil.

Journal of Clinical Pathology

|February 1, 2007

Summary

This study reports the first case of solitary phaeohyphomycosis on a mucosal surface, specifically the lower lip. Fungal elements identified as Alternaria species were found within the lesion.

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Area of Science:

Mycology
Dermatopathology
Infectious Diseases

Background:

Phaeohyphomycosis is a fungal infection characterized by dark-walled hyphae.
Mucosal involvement in phaeohyphomycosis is rare, with most cases occurring on the skin.

Observation:

A solitary lesion was observed on the inferior lip of a 57-year-old female patient.
Histopathological examination revealed granulomatous-purulent inflammation with characteristic brownish fungal structures.

Findings:

Molecular identification through rDNA sequencing confirmed the causative agent as an Alternaria species.
This represents the first documented instance of phaeohyphomycosis affecting the mucosal surface.

Implications:

This case expands the known clinical spectrum of phaeohyphomycosis.
Highlights the importance of considering fungal infections in mucosal lesions.
Suggests Alternaria species can cause mucosal phaeohyphomycosis.