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Published on: July 19, 2013
Detecting cardiac involvement in sarcoidosis: a call for prospective studies of newer imaging techniques
C Pandya1, R C Brunken, P Tchou
1Department of Pulmonary, Allergy and Critical CareMedicine, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Abstract:
Diagnosis of cardiac involvement in sarcoidosis is challenging and usually relies on a combination of clinical findings and imaging abnormalities. The case of a 53-yr-old female is described who presented with ventricular tachycardia and suspected angiosarcoma involving the right atrium and superior vena cava. A combination of magnetic resonance imaging and (18)F-2-fluoro-2-deoxyglucose-positron emission tomography were essential to the diagnosis of cardiac sarcoidosis. Reversibility of the disease was predicted more clearly by (18)F-2-fluoro-2-deoxyglucose-positron emission tomography than by magnetic resonance imaging, and clinical activity was predicted by persistent hypermetabolism on serial (18)F-2-fluoro-2-deoxyglucose-positron emission tomography.
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