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Investigating the Phagocytosis of Leishmania using Confocal Microscopy
Published on: July 29, 2021
Chronic diarrhea and malabsorption caused by Leishmania donovani
Chalamalasetty Sreenivasa Baba1, Govind K Makharia, Purva Mathur
1Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110 029, India.
Abstract:
Chronic diarrhea and malabsorption are uncommon in immunocompetent patients with visceral leishmaniasis. We report two immunocompetent patients with visceral leishmaniasis where the predominant presentation was chronic diarrhea. One of them had clinically overt malabsorption and duodenal mucosa was loaded with Leishmania donovani bodies. The other patient had diffuse colonic aphthous and discrete ulcerations and Leishmania donovani bodies were seen in the crush smears of the colonic mucosa. With amphotericin B, there was reversal of malabsorption and healing of colonic ulcers.
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