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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jul 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Should we screen for asymptomatic left ventricular dysfunction in glaucoma patients?

L Bojic1, R Ermacora, D Karelovic

  • 1Eye Clinic, Clinical Hospital Split, Split University, Split, Croatia. deni@kbsplit.hr

Annals of Saudi Medicine
|February 1, 2007
PubMed
Summary

Primary open-angle glaucoma patients may experience asymptomatic myocardial relaxation dysfunction. This cardiac condition might be linked to systemic vascular dysregulation, warranting further investigation in glaucoma care.

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Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
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Last Updated: Jul 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

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Published on: May 25, 2020

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Area of Science:

  • Cardiology
  • Ophthalmology
  • Vascular Biology

Background:

  • Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
  • Subtle cardiovascular changes may precede overt symptoms in POAG patients.
  • Assessing left ventricular (LV) function in POAG is crucial for comprehensive patient management.

Purpose of the Study:

  • To evaluate the prevalence of asymptomatic left ventricular dysfunction.
  • To investigate potential links between POAG and subclinical cardiac abnormalities.
  • To explore myocardial relaxation patterns in POAG patients compared to controls.

Main Methods:

  • Two-dimensional and pulsed Doppler echocardiography utilized.
  • Transmitral flow parameters assessed in 31 POAG patients and 27 controls.
  • Key echocardiographic indices including ejection fraction (EF) and fractional shortening (FS) measured.

Main Results:

  • No significant differences observed in standard LV systolic function parameters (EF, FS).
  • Significant differences noted in the E/A ratio (P=0.04) and VTIA/VTIE ratio (P=0.05).
  • All measured values remained within normal age-specific confidence limits.

Conclusions:

  • Findings suggest potential myocardial relaxation dysfunction in POAG patients.
  • This dysfunction may be associated with underlying systemic vascular dysregulation.
  • Further research is warranted to elucidate the relationship between glaucoma and cardiac health.