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[Prenatal, perinatal and neonatal factors in infantile autism]
D Kocijan-Hercigonja1, D Remeta, M Orehovac
1Vojne bolnice Zagreb, Psihijatrijske bolnice Jankomir i Skolskog dispanzera Doma zdravlja Susedgrad u Zagrebu.
Insights
Prenatal, perinatal, and neonatal complications show a significant link to autism in children compared to healthy peers. This connection is less pronounced when compared to children with intellectual disabilities, suggesting a complex cause for autism.
Area of Science:
- Developmental Pediatrics
- Neurodevelopmental Disorders
- Autism Spectrum Disorder Etiology
Context:
- Investigating the multifactorial origins of Autism Spectrum Disorder (ASD).
- Examining the role of early life health events in neurodevelopment.
- Comparing risk factors across different neurodevelopmental trajectories.
Purpose:
- To determine the association between prenatal, perinatal, and neonatal complications and the development of autism.
- To compare these associations in autistic children versus healthy controls and children with intellectual disabilities.
Summary:
- A study analyzed prenatal, perinatal, and neonatal complications in autistic children using a specialized questionnaire.
- Results indicate a statistically significant link between certain early life complications and autism when compared to healthy children.
- The association was less significant when compared to children with intellectual disabilities, highlighting the complexity of autism's etiology.
Impact:
- Provides evidence supporting the role of early life factors in autism development.
- Contributes to understanding the complex etiology of autism spectrum disorder.
- Informs future research directions for identifying autism risk factors and potential interventions.
Abstract:
Analysing prenatal, perinatal, and neonatal complications in autistic children by a specially prepared questionnaire, the authors aimed at establishing whether there is a connection between prenatal, perinatal, and neonatal complications and autism in comparison with normal and mentally retarded children. The results have shown that there is a statistically significant connection of some of these factors with autism in relation to the control group of healthy children, while these differences proved less significant in relation to the group of mentally retarded children. The results obtained partly correspond to the results of similar investigations in the world, indicating a complex etiology of autism.