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Related Experiment Video

Updated: Jul 17, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Oral contraceptive and twinning: case-control study.

M M Kotb¹, M A El-Ghannam

¹Community Medicine Department, Faculty of Medicine, Ain Shams University.

The Journal of the Egyptian Public Health Association

|January 1, 1993

Summary

Oral contraceptive (OC) use may increase the risk of twin births. Women conceiving within three months of stopping OCs had a higher chance of having twins.

Area of Science:

Reproductive Endocrinology
Obstetrics and Gynecology
Epidemiology

Background:

Oral contraceptives (OCs) are widely used for family planning.
The potential impact of OC use cessation on conception outcomes, including twinning, requires further investigation.
Understanding factors influencing twinning risk is crucial for reproductive health counseling.

Purpose of the Study:

To investigate the association between oral contraceptive use and the risk of twin deliveries.
To determine if recent cessation of oral contraceptive use influences twinning rates.

Main Methods:

A retrospective case-control study design was employed.
157 women with twin deliveries (cases) were recruited from two Cairo hospitals.
Two controls with singleton deliveries, matched for maternal age and parity, were selected for each case. Data on oral contraceptive use and last menstrual period were collected via interviews.

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Last Updated: Jul 17, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Main Results:

Overall oral contraceptive use prior to the last pregnancy was significantly higher in the twin delivery group compared to controls (P < 0.05).
A statistically significant increased risk of twinning was observed for conceptions occurring within three months of oral contraceptive cessation (Odds Ratio = 2.3, 95% Confidence Interval: 1.2 - 4.4).

Conclusions:

The study suggests a potential increased risk of twinning following oral contraceptive use, particularly with conception shortly after cessation.
These findings highlight the importance of considering recent oral contraceptive history in counseling regarding conception and pregnancy outcomes.