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PDZ domain protein-protein interactions: a case study with PICK1

Kumlesh K Dev1

  • 1Neurosciences, Department of Neurodegeneration, Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, WSJ-386.7.43, CH-4002 Basel, Switzerland. kumlesh_k.dev@novartis.com

Current Topics in Medicinal Chemistry
|February 3, 2007
PubMed
Summary

This review shows how Protein Interacting with C Kinase 1 (PICK1) uses its PDZ domain for protein interactions. These interactions are key for regulating cell functions and are involved in various diseases.

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