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Updated: Oct 21, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

[Regressive changes in the placenta in early pregnancy in women with primary arterial hypertension]

W Lotocki1, E Król, M Drozdzewicz

  • 1Kliniki Ginekologii i Połoznictwa Septycznego, Instytutu Połoznictwa i Chorób Kobiecych AM Białymstoku.

Roczniki Akademii Medycznej W Bialymstoku = Annales Academiae Medicae Bialostocensis
|January 1, 1990
PubMed

Morphological methods, in particular histochemical technique of secondary fluorescence according to Bertalanffy were used for the assessment of regressive changes of placenta. In women with primary arterial hypertension during early pregnancy fibrinoid masses in decidua, chorion, anchoring willi, villous plate, basal plate, villous trunks and terminal villi appear. These changes are followed from one side, by an atrophy of the blood vessels and connective tissue cells, and from the other, there increases the number of decidua giant cells, as well as of syncytium and cytotrophoblast. The areas of impaired blood supply contain giant cells and intervening foam cells. These cells according to the authors can be the forms of regressive changes exhibiting relative biological activity influencing trophic status of the placenta. Possible importance of the fibrinoid masses for the immunology of pregnancy which is developing under maternal morbid conditions has been discussed.

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